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بحران میاستنیک
Although MG is a relatively rare disease (incidence of 4 to 12 per million person years and prevalence of 40 to 180 per million worldwide), it is relevant to neurocritical care in that patients can present acutely in myasthenic crisis with rapid deterioration of muscle function and ventilatory fail- ure.
The myasthenic crisis can be precipitated by a progres- sion in severity of the disease state or often by amplification by another factor.
Many drugs can exacerbate myasthenic crisis, including amino- glycosides, fluoroquinolones, anticonvulsants (including phenytoin), steroids, β-blockers, calcium channel antago- nists, ketamine, lidocaine, neuromuscular blockers, and anticholinergic agents.249
Myasthenia gravis: management of myasthenic crisis and perioperative care.
The role of non- invasive ventilation and factors predicting extubation outcome in myasthenic crisis.
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